منابع مشابه
Cilia-related diseases.
There are at least eight categories of cilia in the human body and malfunctioning of any one or several of them will have different consequences for the patient. A genetic error of the respiratory cilia (9 + 2) is the cause of the airways disease named immotile-cilia syndrome (or PCD), whereas defective ependymal cilia (9 + 2) carries an increased risk of hydrocephalus. When the so-called nodal...
متن کاملCilia and Diseases
In recent decades, cilia have moved from relative obscurity to a position of importance for understanding multiple complex human diseases. Now termed the ciliopathies, these diseases inflict devastating effects on millions of people worldwide. In this review, written primarily for teachers and students who may not yet be aware of the recent exciting developments in this field, we provide a gene...
متن کاملCilia/Ift protein and motor -related bone diseases and mouse models.
Primary cilia are essential cellular organelles projecting from the cell surface to sense and transduce developmental signaling. They are tiny but have complicated structures containing microtubule (MT)-based internal structures (the axoneme) and mother centriole formed basal body. Intraflagellar transport (Ift) operated by Ift proteins and motors are indispensable for cilia formation and funct...
متن کاملAsbestos-related Lung Diseases: A Brief Update
Health risks from asbestos exposures have been evaluated, considering past professional histories when exposures at workplaces were higher than today. A linear no-threshold (LNT) model has been applied, although its relevance is unproven. Fibers are often found in the lungs and pleura of deceased people. Fiber findings do not prove that a disease is caused by asbestos. It is reasonable to assum...
متن کاملWork-Related physical activity and coronary diseases
Introduction: Prevalence of cardiovascular disease (CVD) is increasing in the world. Modernization and reduction of physical activity in present century and also controversial results about relationship between work-related physical activity and CVD, lead to investigate the relationship between work-related physical activity and CVD. Methods: This cross-sectional study is based on data from f...
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ژورنال
عنوان ژورنال: The Journal of Pathology
سال: 2004
ISSN: 0022-3417
DOI: 10.1002/path.1652